STATISTICAL QUESTION Nested case-control studies: advantages and disadvantages
نویسنده
چکیده
Researchers investigated whether antipsychotic drugs were associated with venous thromboembolism. A population based nested case-control study design was used. Data were taken from the UK QResearch primary care database consisting of 7 267 673 patients. Cases were adult patients with a first ever record of venous thromboembolism between 1 January 1996 and 1 July 2007. For each case, up to four controls were identified, matched by age, calendar time, sex, and practice. Exposure to antipsychotic drugs was assessed on the basis of prescriptions on, or during the 24months before, the index date. 1
منابع مشابه
بررسی روند مطالعات مورد ـ شاهد لانه گزیده و مقایسه‌ی آن با مطالعات هم‌گروهی و مورد ـ شاهد از سال 2005 ـ 1996
Background & Objectives: This investigation was prompted by the growing importance of nested case-control studies and the increasing frequency with which they are done in epidemiologic research. After a brief explanation of nested case-control studies, we evaluate the trends in research methodology over the last decade, especially with regard to cohort, case-control, and nested case-control des...
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متن کاملA relative power table for nested matched case-control studies.
OBJECTIVE To calculate relative powers for nested case-control studies for different values of both relative risk and numbers of controls per case, given a fixed number of cases available for analysis. METHODS Algebraic and numerical methods. RESULTS In nested case-control studies, statistical power is a function of relative risk, rarity of exposure, number of case-control sets, and the num...
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تاریخ انتشار 2014